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Journavx (suzetrigine) is a sodium channel blocker that helps alleviate moderate-to-severe acute pain in adults by decreasing pain signals before they reach the brain and are felt as pain.

This medication works outside the brain in your peripheral nervous system and is a nonopioid medication, meaning it is not expected to be addictive.

Journavx 50 mg tablets for oral administration are available with a doctor’s valid prescription.

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Directions

Follow your doctor’s instructions on how to take Journavx. Swallow the tablets whole, refrain from chewing or crushing them. Grapefruit-containing food and drinks should be avoided during treatment with Journavx.

Journavx tablets should be stored between 20°C-25°C (68°F-77°F).

Refer to the medication guide that accompanies your prescription for additional usage information.

Have questions or concerns? Do not hesitate to reach out to your doctor or pharmacist.

Ingredients

Active ingredient: suzetrigine

Inactive ingredients: croscarmellose sodium, hypromellose acetate succinate, magnesium stearate, microcrystalline cellulose, FD&C Blue #2 aluminum lake, polyethylene glycol, polyvinyl alcohol-partially hydrolyzed, talc, and titanium dioxide

Contraindications

Do not combine Journavx with strong CYP3A inhibitors. If you are unsure about your medications, check with your doctor.

Cautions

It is important to talk to your doctor about the following prior to Journavx initiation:
All the medications you are currently taking. These include both over-the-counter and prescription medications.
Any allergies you may have
Existing health conditions
Prior medical history
Status of pregnancy or breastfeeding
Journavx is not recommended for patients with severe liver impairment. Those with moderate liver impairment may be at increased risk of adverse reactions when using this medication.

Side Effects

Common Journavx side effects include muscle spasms, itching, rash, and increased creatine phosphokinase. However, other side effects may also be possible. If you experience any side effects while taking Journavx, consult your doctor.

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